Tuesday, January 22, 2008

Key Bone Building Pathway Identified in Mice

Source: University of California, San Francisco
Date: January 22, 2008

Summary:

Researchers at the San Francisco VA Medical Center, University of California, San Francisco, and Gladstone Institute of Cardiovascular Disease have uncovered a biochemical signaling pathway that leads to the formation of abnormally large bones in mice. For humans, the discovery may provide clues to both childhood bone formation and osteoporosis –– the loss of bone in old age –– as well as a path to improved osteoporosis treatments. The research is detailed in a paper in the online Early Edition of the Proceedings of the National Academy of Sciences.