Thursday, March 11, 2010

Discovery of Cellular "Switch" May Provide New Means of Triggering Cell Death, Treating Human Diseases

Source: University of Colorado at Boulder
Date: March 11, 2010

Summary:

The discovery of a novel cellular “switch” in the popular laboratory research worm, C. elegans, by a University of Colorado at Boulder team may provide researchers with a new means of triggering programmed cell death in humans to treat disease.
A research team led by the University of Colorado at Boulder has discovered a previously unknown cellular "switch" that may provide researchers with a new means of triggering programmed cell death, findings with implications for treating cancer.

The new results are a big step forward in understanding programmed cell death, or apoptosis, a cell suicide process that involves a series of biochemical events leading to changes like cell body shrinkage, mitochondria destruction and chromosome fragmentation, said CU-Boulder Professor Ding Xue. But unlike traumatic cell death from injury, programmed cell death is a naturally occurring aspect of animal development that may help prevent human diseases like cancer and autoimmune disorders, said Xue, lead author on the new study.