Tuesday, October 19, 2010

Bioelectrical Signals Turn Stem Cells' Progeny Cancerous

Source: Tufts University
Date: October 19, 2010

Summary:

Biologists at Tufts University School of Arts and Sciences have discovered that a change in membrane voltage in newly identified "instructor cells" can cause stem cells' descendants to trigger melanoma-like growth in pigment cells. The Tufts team also found that this metastatic transformation is due to changes in serotonin transport. The discovery could aid in the prevention and treatment of diseases like cancer and vitiligo as well as birth defects. The research is reported in the October 19, 2010, issue of Disease Models and Mechanisms.