Tuesday, October 19, 2010

Scientists Generate Functional Nerve Cells from Adult Skin Cells

Source: University of Connecticut
Date: October 19, 2010

Summary:

Scientists at the University of Connecticut Health Center have successfully converted stem cells derived from the adult skin cells of four humans into region-specific forebrain, midbrain, and spinal cord neurons (nerve cells) with functions. The research is a key step toward realizing the cells’ potential to treat various neurodegenerative diseases. Their study was published in PLoS ONE, an international, peer-reviewed online journal of the non-profit Public Library of Science (PLoS) and describes how scientists used cell reprogramming protocols to first transform the adult tissue into "induced pluripotent stem cells" that are all but identical to embryonic stem cells.