Source: Cell Press
Posted: April 23, 2006
Two studies are providing new details of the "genetic program" that enables embryonic stem cells to become any cell type in the body. Both groups identified mechanisms that keep the embryonic stem cells of mice or humans from choosing a specific formation path--such as muscle or nervous tissue--while remaining "poised for activation."
The study suggests that a comprehensive inventory of the presence or absence of bivalent domains over key developmental genes may provide new insight into cell identity and differentiation potential, in both health and disease.
Commetary: Hopefully this research will further understanding about embryonice stem cell development and provide scientists with new strategies to apply embryonic stem cells to treat diseases and injuries.
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