Tuesday, April 18, 2006

Purdue Scientists Find Hypertension Drug Reverses Death Of Cells

Source: Purdue University
Posted: April 18, 2006

Purdue University researchers have identified a drug commonly used to treat hypertension that may also reverse damage from spinal cord injuries, cancer and Parkinson's disease.

The Researchers found that hydralazine, a medication that relaxes veins and arteries, may be an antidote for acrolein, a deadly toxin that is produced after a nerve cell is injured.

The researchers studied how acrolein attacks and kills cells and showed that cell death caused by acrolein (a-KRO-le-an), a byproduct of an injury, can be reversed when hydralazine is administered.

Commentary: These studies seem to be signficant findings into understanding and potentially reversing cell death, and could potentially provide new insights into cellular regeneratiion to treat conditions such as Alzheimer's Disease, Parkinson's Disease, diabetes and stroke.

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