Friday, April 07, 2006

Mutation In Blood Stem Cells Provides Clues To Cancer Development

Source: University of California - San Diego
Posted: April 7, 2006

A mutation in blood stem cells occurs in patients with a blood disorder called polycythemia vera (PV), scientists at the Moores Cancer Center at the University of California, San Diego (UCSD) and the Institute for Stem Cell Biology and Regenerative Medicine and Comprehensive Cancer Center at Stanford University School of Medicine have confirmed.

The discovery suggests that development of a very specific inhibitor at the stem-cell level, to interfere with the pathway leading to the disease, could improve treatment for the cancer-causing disorder. The advance may enable scientist fight the disease by destroying cancerous stem cells while still enabling normal stem cell production, protection and differentiation and health of stem cells.

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