Thursday, July 27, 2006

Promising Therapy For ALS Delivers Antisense Drug Directly To Nervous System

Source: University of California - San Diego
Posted: July 27, 2006

Summary:

Researchers have created and tested a molecular therapy in animals that they hope will be a significant advancement in the development of effective treatments for amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease. The study shows that therapeutic molecules known as antisense oligonucleotides can be delivered to the brain and spinal cord through the cerebrospinal fluid (CSF) at doses shown to slow the progression of ALS in rats.

Hopefully this therapy can eventually be translated into an effective human treatment for amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, as well as other neuro-muscular diseases in humans.

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